Scientific Communication Projects
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Journal club presentation
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CRISPR/Cas9 gene editing of CFTR gene in organoid
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Biotechnology technique (Cre-LoxP)
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Bio-Business business simulation website Gentech
Journal Club Presentation
As part of the master's degree journal club discussions, this is a presentation based on the article “Eriodictyol as a Potential Candidate Inhibitor of Sortase A Protects Mice From Methicillin-Resistant Staphylococcus aureus-Induced Pneumonia.”I selected this paper to showcase how the same research can be communicated effectively through both poster and oral formats. The presentation highlighted eriodictyol as a natural anti-virulence compound capable of inhibiting Sortase A in S. aureus and protecting mice from MRSA-induced pneumonia. It summarised the study’s background, the mechanism of action of Sortase A, key experimental results, major conclusions, and the broader potential of anti-virulence strategies as emerging alternatives to traditional antibiotics.
The presentation was done in class. This is a re-recorded version created specially for this website, summarizing the key learnings and discussion from the article on anti-virulent agent eriodictyol.
CRISPR/Cas9 gene editing of CFTR gene in intestinal organoid presentation
"Functional Repair of CFTR by CRISPR/Cas9 in Intestinal Stem Cell Organoids of Cystic Fibrosis Patients."
This presentation project involved analyzing and presenting the landmark study “Functional Repair of CFTR by CRISPR/Cas9 in Intestinal Stem Cell Organoids of Cystic Fibrosis Patients.” I explored the biology of the CFTR gene, the development of intestinal organoids pioneered by Prof. Hans Clevers, and the molecular mechanism of CRISPR/Cas9 as a gene-editing tool. The presentation discussed how patient-derived organoids were engineered – similar to how gene editing is applied in 2D cell cultures, the methodology used to repair the CFTR mutation, the experimental results, and broader implications for advancing gene-therapy applications using organoid systems.
A brief video of CRISPR/Cas9-mediated CFTR correction in cystic fibrosis organoids, covering methodology, results, and gene-therapy relevance.
A beautiful genetic tool Cre-LoxP presentation
This project involved creating and delivering a live presentation explaining how the Cre-LoxP system functions as a genetic manipulation tool and how it is used to generate conditional knockout mice. The presentation outlined the types of biological questions this technique can address—such as investigating gene function in specific tissues or developmental stages—and highlighted its advantages over traditional whole-organism knockouts. It provided a clear explanation of the molecular mechanism, with Cre recombinase recognising LoxP sites and excising the DNA between them, and demonstrated its real-world application through the article “Ablation of huntingtin in adult neurons is nondeleterious but its depletion in young mice causes acute pancreatitis.”
The presentation was done in class. A presentation on how Cre-LoxP enables conditional gene deletion, illustrated through a real research example.
A Bio-Business Simulation Set-up in Biotechnology industry
This project simulated real-world decision-making within the biotechnology sector, requiring our team to establish a new biotech company (Gentech) from the ground up and design a viable product for market launch. Our company focused on developing a HER2-targeting monoclonal antibody for breast cancer—mirroring the complexities of real biopharmaceutical development. The simulation integrated market research, R&D planning, regulatory considerations, financial strategy, and commercialization pathways. I began as the Market Researcher and later stepped into the role of Chief Executive Officer during the production phase.
As CEO and group leader, I coordinated the team’s workflow, set weekly agendas, and ensured consistent progress toward key milestones. I provided direction when challenges arose, clarified uncertainties, and engaged lecturers for strategic alignment when required. My aim was to maintain high standards, foster effective teamwork, and guide the group in making informed, timely decisions. Importantly, the entire project website was designed, developed, and led by me, ensuring a cohesive, clear, and professional final presentation.
In my Market Researcher role, I conducted a comprehensive analysis of the HER2-positive breast cancer market, including patient segmentation, market size, pricing strategy, sales projections, and competitive landscape evaluation. Beyond my assigned responsibilities, I also contributed to product development strategy, brand graphic design, website graphics, video production and editing, website creation, the business model canvas, and P&L planning. These additional contributions strengthened the strategic direction and cohesiveness of the team’s output, reflecting my commitment to quality, leadership, and multidisciplinary collaboration
